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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
Data
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UST transfers sulfate to (2-)GlcA-GalNAc-6-sulfate

C6S-PG + PAPS → C2S6S-PG + PAP + H+

Reactome
R-HSA-9941305
Compartment
Golgi lumen
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • chondroitin 2-O-sulfotransferase activity of UST [Golgi membrane]UniProt Q9Y2C2

Literature

  1. Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate J Biol Chem, 1999
  2. Mutational study of heparan sulfate 2-O-sulfotransferase and chondroitin sulfate 2-O-sulfotransferase J Biol Chem, 2007