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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

FAM20B phosphorylates Xyl moiety

GlcA-Gal-Gal-Xyl-proteins + ATP → GlcA-Gal-Gal-XylP-proteins + ADP + H+

Reactome: R-HSA-9941039
Compartment: Golgi lumen
Rhea: RHEA:19462

Inputs

GlcA-Gal-Gal-Xyl-proteinsR-HSA-2064225, Golgi lumen
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

GlcA-Gal-Gal-XylP-proteinsR-HSA-9941158, Golgi lumen
ADPCHEBI:456216, C10H12N5O10P2, cytosol
H+CHEBI:15378, H, Golgi lumen

Catalysed by

phosphotransferase activity, alcohol group as acceptor of FAM20B [Golgi membrane]EC 2.7.1; UniProt O75063

Literature

FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region Biochem J, 2009
Chondroitin sulfate metabolism in the brain Acta Neurobiol Exp (Wars), 2019