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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

mito-STARD7 transports Q10 to outer mitochondrial membrane

CoQH2 → CoQH2

Reactome: R-HSA-9856502
Compartment: mitochondrial inner membrane · mitochondrial outer membrane
Rhea: None recorded

Inputs

CoQH2CHEBI:64183, C59H92O4, mitochondrial inner membrane

Outputs

CoQH2CHEBI:64183, C59H92O4, mitochondrial outer membrane

Catalysed by

lipid transfer activity of mito-STARD7 [mitochondrial outer membrane]UniProt Q9NQZ5

Literature

Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7 Nat Cell Biol, 2023
New Insights on the Uptake and Trafficking of Coenzyme Q Antioxidants (Basel), 2023
UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae Nat Commun, 2021