Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

B3GNT5 transfers GlcNAc to LacCer

LacCer-d18 + UDP-GlcNAc → Lc3Cer + UDP + H+

Reactome: R-HSA-9846501
Compartment: Golgi lumen · Golgi membrane
Rhea: RHEA:13905

Inputs

LacCer-d18CHEBI:17950, C31H56NO13R, Golgi membrane
UDP-GlcNAcCHEBI:57705, C17H25N3O17P2, Golgi lumen

Outputs

Lc3CerCHEBI:17103, C39H69N2O18R, Golgi membrane
UDPCHEBI:58223, C9H11N2O12P2, Golgi lumen
H+CHEBI:15378, H, Golgi lumen

Catalysed by

lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity of B3GNT5 [Golgi membrane]EC 2.4.1.206; UniProt Q9BYG0

B3GNT5 transfers GlcNAc to LacCer

Inputs

Outputs

Catalysed by

Literature