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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

A4GALT transfers galactose to LacCer

LacCer-d18 + UDP-Gal → Gb3Cer + UDP + H+

Reactome: R-HSA-9846477
Compartment: Golgi membrane · Golgi lumen
Rhea: RHEA:11924

Inputs

LacCer-d18CHEBI:17950, C31H56NO13R, Golgi membrane
UDP-GalCHEBI:66914, C15H22N2O17P2, Golgi lumen

Outputs

Gb3CerCHEBI:18313, C37H66NO18R, Golgi membrane
UDPCHEBI:58223, C9H11N2O12P2, Golgi lumen
H+CHEBI:15378, H, Golgi lumen

Catalysed by

lactosylceramide 4-alpha-galactosyltransferase activity of A4GALT [Golgi membrane]EC 2.4.1.228; UniProt Q9NPC4

A4GALT transfers galactose to LacCer

Inputs

Outputs

Catalysed by

Literature