Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

FUT1,2 transfer fucose to gangliosides

GM1,GA1 + GDP-Fuc → Fuc-GM1, Fuc-GA1 + GDP + H+

Reactome: R-HSA-9846332
Compartment: Golgi lumen · Golgi membrane
Rhea: None recorded

Inputs

GM1,GA1R-ALL-9846337, Golgi membrane
GDP-FucCHEBI:57273, C16H23N5O15P2, Golgi lumen

Outputs

Fuc-GM1, Fuc-GA1R-ALL-9846331, Golgi membrane
GDPCHEBI:58189, C10H12N5O11P2, Golgi lumen
H+CHEBI:15378, H, Golgi lumen

Catalysed by

fucosyltransferase activity of FUT1,2 [Golgi membrane]EC 2.4.1

FUT1,2 transfer fucose to gangliosides

Inputs

Outputs

Catalysed by

Literature