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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ST6GALNAC5,6 transfer Neu5Ac to GM1b

GM1b + CMP-Neu5Ac → GD1alpha + CMP + H+

Reactome: R-HSA-9846305
Compartment: Golgi lumen · Golgi membrane
Rhea: RHEA:41968

Inputs

GM1bCHEBI:78568, C56H95N3O31R, Golgi membrane
CMP-Neu5AcCHEBI:57812, C20H29N4O16P, Golgi lumen

Outputs

GD1alphaCHEBI:78569, C67H111N4O39R, Golgi membrane
CMPCHEBI:60377, C9H12N3O8P, Golgi lumen
H+CHEBI:15378, H, Golgi lumen

Catalysed by

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity of ST6GALNAC5,6 [Golgi membrane]EC 2.4.3.3

ST6GALNAC5,6 transfer Neu5Ac to GM1b

Inputs

Outputs

Catalysed by

Literature