GAL3ST1 transfers sulfate to GalCer,LacCer
PAPS + GalCer,LacCer → PAP + H+ + SM3,SM4
- Reactome
- R-HSA-9844587
- Compartment
- Golgi membrane
- Rhea
- None recorded
Inputs
- PAPSCHEBI:58339, C10H11N5O13P2S, Golgi lumen
- GalCer,LacCerR-ALL-9845491, Golgi membrane
Outputs
- PAPCHEBI:58343, C10H11N5O10P2, Golgi lumen
- H+CHEBI:15378, H, Golgi lumen
- SM3,SM4R-ALL-9845488, Golgi membrane
Catalysed by
- galactosylceramide sulfotransferase activity of GAL3ST1 [Golgi membrane]EC 2.8.2.11; UniProt Q99999
Literature
- Molecular cloning and expression of cDNA encoding human 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase J Biol Chem, 1997
- Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells J Biochem, 1996
- Biosynthesis and biological function of sulfoglycolipids Proc Jpn Acad Ser B Phys Biol Sci, 2013