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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PSAP(195-273) forms a dimer

2 PSAP(195-273) → PSAP(195-273) dimer

Reactome: R-HSA-9840488
Compartment: lysosomal lumen
Rhea: None recorded

Inputs

2 PSAP(195-273)R-HSA-9840336, lysosomal lumen

Outputs

PSAP(195-273) dimerR-HSA-9840482, lysosomal lumen

Literature

Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B Protein Expr Purif, 2003
Structural analysis of saposin C and B. Complete localization of disulfide bridges J Biol Chem, 1995
Crystal structure of saposin B reveals a dimeric shell for lipid binding Proc Natl Acad Sci U S A, 2003