An unknown BILR reduces BIL to D-UBGN
BIL + a reduced electron acceptor → D-UBGN + an oxidized electron acceptor
- Reactome
- R-HSA-9661745
- Compartment
- extracellular region
- Rhea
- None recorded
Inputs
- BILCHEBI:57977, C33H34N4O6, extracellular region
- a reduced electron acceptorCHEBI:17654, extracellular region
Outputs
- D-UBGNCHEBI:4260, C33H42N4O6, extracellular region
- an oxidized electron acceptorCHEBI:17654, extracellular region
Catalysed by
- oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor of BILR [extracellular region]EC 1.3.1
Literature
- Synthesis of urobilinogen by broken cell preparations of intestinal bacteria Gastroenterology, 1968
- Preferential reduction of conjugated bilirubin to urobilinogen by normal fecal flora Proc. Soc. Exp. Biol. Med., 1958
- Identification of bilirubin reduction products formed by Clostridium perfringens isolated from human neonatal fecal flora J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006
- Reduction of bilirubin ditaurate by the intestinal bacterium Clostridium perfringens Acta Biochim. Pol., 2012