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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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HEXB cleaves the terminal GlcNAc from small HA fragments

H2O + GlcNAc-GlcA-GlcNAc → GlcNAc + GlcA-β1,3-GlcNAc

Reactome
R-HSA-9638076
Compartment
lysosomal lumen
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • beta-N-acetylhexosaminidase activity of bHEXB [lysosomal lumen]EC 3.2.1.52

Literature

  1. Oligosaccharide structure and amino acid sequence of the major glycopeptides of mature human beta-hexosaminidase Biochemistry, 1988