Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Sulfhydrylation and ring cleavage of precursor Z

Precursor Z + H2O + 2xMOCS2-CO-S(1-):2xMOCS2B → MPT + H+ + 2xMOCS2A:2xMOCS2B

Reactome: R-HSA-947541
Compartment: cytosol
Rhea: None recorded

Inputs

Precursor ZCHEBI:59648, C10H11N5O7P, cytosol
H2OCHEBI:15377, H2O, cytosol
2xMOCS2-CO-S(1-):2xMOCS2BR-HSA-947582, cytosol

Outputs

MPTCHEBI:58698, C10H11N5O6PS2, cytosol
H+CHEBI:15378, H, cytosol
2xMOCS2A:2xMOCS2BR-HSA-947569, cytosol

Catalysed by

molybdopterin synthase activity of 2xMOCS2-CO-S(1-):2xMOCS2B [cytosol]EC 2.8.1.12

Sulfhydrylation and ring cleavage of precursor Z

Inputs

Outputs

Catalysed by

Literature