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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA

17(S)-Hp-DHA + O2 → 7(S),17(S)-diHp-DHA

Reactome: R-HSA-9026918
Compartment: cytosol
Rhea: None recorded

Inputs

17(S)-Hp-DHACHEBI:133795, C22H31O4, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

7(S),17(S)-diHp-DHACHEBI:140349, C22H31O6, cytosol

Catalysed by

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen of Lipoxygenase [cytosol]EC 1.13.11

Literature

Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways FASEB J., 2015