Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3

DPAn-3 + O2 + hydrogen donor → 13(R)-HDPAn-3 + hydrogen acceptor + H2O

Reactome: R-HSA-9026408
Compartment: cytosol · endoplasmic reticulum membrane
Rhea: RHEA:48853

Inputs

DPAn-3CHEBI:77224, C22H33O2, cytosol
O2CHEBI:15379, O2, cytosol
hydrogen donorCHEBI:17499, H2A, cytosol

Outputs

13(R)-HDPAn-3CHEBI:90824, C22H33O3, cytosol
hydrogen acceptorCHEBI:13193, A, cytosol
H2OCHEBI:15377, H2O, cytosol

Catalysed by

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen of PTGS2 dimer [endoplasmic reticulum membrane]EC 1.13.11

PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3

Inputs

Outputs

Catalysed by

Literature