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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4

13(R)-HDPAn-3 + O2 → RvT1-4

Reactome
R-HSA-9026405
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of ALOX5 [cytosol]EC 1.13; UniProt P09917

Literature

  1. Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections Nat. Med., 2015
  2. Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins J. Nat. Prod., 2016