Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3

17(S)-Hp-DPAn-3 + O2 → 7,17-diHp-DPAn-3

Reactome: R-HSA-9025996
Compartment: cytosol
Rhea: None recorded

Inputs

17(S)-Hp-DPAn-3CHEBI:140291, C22H33O4, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

7,17-diHp-DPAn-3CHEBI:140381, C22H33O6, cytosol

Catalysed by

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of ALOX5 [cytosol]EC 1.13; UniProt P09917

Literature

Novel n-3 immunoresolvents: structures and actions Sci Rep, 2013