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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1

7(S),14(S)-diHp-DHA + reduced acceptor → 7-epi-MaR1 + oxidised acceptor

Reactome: R-HSA-9025007
Compartment: cytosol
Rhea: None recorded

Inputs

7(S),14(S)-diHp-DHACHEBI:140196, C22H32O6, cytosol
reduced acceptorR-ALL-5359016, cytosol

Outputs

7-epi-MaR1CHEBI:140350, C22H31O4, cytosol
oxidised acceptorR-ALL-9024637, cytosol

Catalysed by

oxidoreductase activity of Hydroperoxy reductase [cytosol]EC 1

Literature

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions J. Exp. Med., 2009
Specialized pro-resolving lipid mediators in the inflammatory response: An update Biochim. Biophys. Acta, 2010