LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1
16S,17S-epoxy-DHA + H2O → (N)PD1
- Reactome
- R-HSA-9024890
- Compartment
- cytosol
- Rhea
- None recorded
Inputs
- 16S,17S-epoxy-DHACHEBI:140313, C22H29O3, cytosol
- H2OCHEBI:15377, H2O, cytosol
Outputs
- (N)PD1CHEBI:195348, C22H31O4, cytosol
Catalysed by
- epoxide hydrolase activity of LTA4H:Zn2+ [cytosol]EC 3.3.2.10
Literature
- Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes J. Immunol., 2006
- Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation J. Biol. Chem., 2003