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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
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Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ALOX15 oxidises 17(S)-Hp-DHA to PDX

17(S)-Hp-DHA + O2 → PDX

Reactome: R-HSA-9024872
Compartment: cytosol
Rhea: None recorded

Inputs

17(S)-Hp-DHACHEBI:133795, C22H31O4, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

PDXCHEBI:138653, C22H32O4, cytosol

Catalysed by

arachidonate 15-lipoxygenase activity of ALOX15 [cytosol]EC 1.13.11.33; UniProt P16050

ALOX15 oxidises 17(S)-Hp-DHA to PDX

Inputs

Outputs

Catalysed by

Literature