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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
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Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA

DHA + O2 → 14(S)-Hp-DHA

Reactome: R-HSA-9020274
Compartment: cytosol
Rhea: None recorded

Inputs

DHACHEBI:77016, C22H31O2, cytosol
O2CHEBI:15379, O2, cytosol

Outputs

14(S)-Hp-DHACHEBI:140279, C22H31O4, cytosol

Catalysed by

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen of ALOX12:Fe2+ [cytosol]EC 1.13.11

ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA

Inputs

Outputs

Catalysed by

Literature