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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA

DHA + O2 → 17(R)-Hp-DHA

Reactome
R-HSA-9020261
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of Ac-PTGS2 dimer [endoplasmic reticulum membrane]EC 1.13

Literature

  1. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals J. Exp. Med., 2002
  2. Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation J. Biol. Chem., 2007