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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

HRSP12 deaminates 2-iminobutanoate to 2OBUTA

2-iminobutanoate + H2O → 2OBUTA + NH4+

Reactome: R-HSA-9014641
Compartment: cytosol
Rhea: RHEA:39976

Inputs

2-iminobutanoateCHEBI:76545, C4H7NO2, cytosol
H2OCHEBI:15377, H2O, cytosol

Outputs

2OBUTACHEBI:16763, C4H5O3, cytosol
NH4+CHEBI:28938, H4N, cytosol

Catalysed by

2-iminobutanoate deaminase activity of HRSP12 [cytosol]UniProt P52758

Literature