Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer

Gb3Cer + UDP-GalNAc → Gb4Cer + UDP + H+

Reactome: R-HSA-8878914
Compartment: Golgi lumen · Golgi membrane
Rhea: None recorded

Inputs

Gb3CerCHEBI:18313, C37H66NO18R, Golgi membrane
UDP-GalNAcCHEBI:57847, C17H25N3O17P2, Golgi lumen

Outputs

Gb4CerCHEBI:88167, C30H50N2O23R2, Golgi membrane
UDPCHEBI:58223, C9H11N2O12P2, Golgi lumen
H+CHEBI:15378, H, Golgi lumen

Catalysed by

galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity of B3GALNT1 [Golgi membrane]EC 2.4.1.79; UniProt O75752

B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer

Inputs

Outputs

Catalysed by

Literature