Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

NMRK2 phosphorylates NAR to yield NAMN

NAR + ATP → ADP + H+ + NAMN

Reactome: R-HSA-8869607
Compartment: cytosol
Rhea: RHEA:25569

Inputs

NARCHEBI:58527, C11H13NO6, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

ADPCHEBI:456216, C10H12N5O10P2, cytosol
H+CHEBI:15378, H, cytosol
NAMNCHEBI:57502, C11H12NO9P, cytosol

Catalysed by

nicotinate riboside kinase activity of NMRK2 [cytosol]EC 2.7.1.173; UniProt Q9NPI5

NMRK2 phosphorylates NAR to yield NAMN

Inputs

Outputs

Catalysed by

Literature