glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP
PYGM dimer, b form + 2 ATP → PYGM dimer a form + 2 ADP + 2 H+
- Reactome
- R-HSA-71541
- Compartment
- cytosol
- Rhea
- RHEA:17990
Inputs
- PYGM dimer, b formR-HSA-71538, cytosol
- 2 ATPCHEBI:30616, C10H12N5O13P3, cytosol
Outputs
- PYGM dimer a formR-HSA-71513, cytosol
- 2 ADPCHEBI:456216, C10H12N5O10P2, cytosol
- 2 H+CHEBI:15378, H, cytosol
Catalysed by
- phosphorylase kinase activity of phosphorylase kinase complex (PHKM) [cytosol]EC 2.7.11.19
Literature
- Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure Front Biosci, 1999
- Muscle glycogenosis with low phosphorylase kinase activity: mutations in PHKA1, PHKG1 or six other candidate genes explain only a minority of cases Eur J Hum Genet, 2003
- Correlation between subunit interactions and enzymatic activity of phosphorylase a. Method for determining equilibrium constants from initial rate measurements Biochemistry, 1970
- Enzymic conversion of phosphorylase a to phosphorylase b Biochim Biophys Acta, 1953