Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2

2MBUT-CoA + FAD + H+ → tiglyl-CoA + FADH2

Reactome: R-HSA-70800
Compartment: mitochondrial matrix
Rhea: RHEA:43781

Inputs

2MBUT-CoACHEBI:156439, C26H40N7O17P3S, mitochondrial matrix
FADCHEBI:57692, C27H30N9O15P2, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Outputs

tiglyl-CoACHEBI:57337, C26H38N7O17P3S, mitochondrial matrix
FADH2CHEBI:58307, C27H33N9O15P2, mitochondrial matrix

Catalysed by

acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix]EC 1.3.99.3

alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2

Inputs

Outputs

Catalysed by

Literature