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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

carbamoyl phosphate + ornithine => citrulline + orthophosphate

CAP + L-Orn → L-Cit + Pi + H+

Reactome: R-HSA-70560
Compartment: mitochondrial matrix
Rhea: RHEA:19514

Inputs

CAPCHEBI:58228, CH2NO5P, mitochondrial matrix
L-OrnCHEBI:46911, C5H13N2O2, mitochondrial matrix

Outputs

L-CitCHEBI:57743, C6H13N3O3, mitochondrial matrix
PiCHEBI:43474, HO4P, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Catalysed by

ornithine carbamoyltransferase activity of OTC trimer [mitochondrial matrix]EC 2.1.3.3

carbamoyl phosphate + ornithine => citrulline + orthophosphate

Inputs

Outputs

Catalysed by

Literature