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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ALDH3B2 oxidises HXAL to PALM

HXAL + H2O + NAD+ → PALM + NADH + H+

Reactome: R-HSA-6808464
Compartment: lipid droplet · cytosol
Rhea: RHEA:33739

Inputs

HXALCHEBI:17600, C16H32O, lipid droplet
H2OCHEBI:15377, H2O, cytosol
NAD+CHEBI:57540, C21H26N7O14P2, cytosol

Outputs

PALMCHEBI:7896, C16H31O2, lipid droplet
NADHCHEBI:57945, C21H27N7O14P2, cytosol
H+CHEBI:15378, H, cytosol

Catalysed by

aldehyde dehydrogenase [NAD(P)+] activity of ALDH3B2 [lipid droplet]EC 1.2.1.5; UniProt P48448

Literature

Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1 Biochim. Biophys. Acta, 2013
Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification Biochem. J., 2015