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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX

R-NADPHX → S-NADPHX

Reactome
R-HSA-6806966
Compartment
mitochondrial matrix
Rhea
RHEA:32216

Inputs

  • R-NADPHXCHEBI:64075, C21H29N7O15P2, mitochondrial matrix

Outputs

  • S-NADPHXCHEBI:64074, C21H29N7O15P2, mitochondrial matrix

Catalysed by

  • NAD(P)HX epimerase activity of APOA1BP dimer [mitochondrial matrix]EC 5.1.99.6

Literature

  1. Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I Genomics, 2002
  2. Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair J. Biol. Chem., 2011