Skip to content

DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

BCKDK phosphorylates BCKDH

BCKDH + 2 ATP → p-BCKDH + 2 ADP + H+

Reactome: R-HSA-5693148
Compartment: mitochondrial matrix
Rhea: RHEA:17302

Inputs

BCKDHR-HSA-70019, mitochondrial matrix
2 ATPCHEBI:30616, C10H12N5O13P3, mitochondrial matrix

Outputs

p-BCKDHR-HSA-5693120, mitochondrial matrix
2 ADPCHEBI:456216, C10H12N5O10P2, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Catalysed by

protein kinase activity of BCKDK dimer [mitochondrial matrix]

Literature