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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ABCC2 transports BMG,BDG from cytosol to extracellular region

BMG,BDG + ATP + H2O → BMG,BDG + ADP + Pi

Reactome: R-HSA-5679041
Compartment: cytosol · extracellular region · plasma membrane
Rhea: None recorded

Inputs

BMG,BDGR-ALL-5679042, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol
H2OCHEBI:15377, H2O, cytosol

Outputs

BMG,BDGR-ALL-5679034, extracellular region
ADPCHEBI:456216, C10H12N5O10P2, cytosol
PiCHEBI:43474, HO4P, cytosol

Catalysed by

bilirubin transmembrane transporter activity of ABCC2 [plasma membrane]UniProt Q92887

Literature

Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2 Hepatology, 1999