Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

An unknown protease degrades ACACB

Btn-ACACB:2Mn2+ → BCTN

Reactome: R-HSA-4167501
Compartment: cytosol · mitochondrial outer membrane
Rhea: None recorded

Inputs

Btn-ACACB:2Mn2+R-HSA-2993829, mitochondrial outer membrane

Outputs

BCTNCHEBI:195545, C16H28N4O4S, cytosol

Catalysed by

peptidase activity of unknown peptidase [cytosol]EC 3.4

Literature

Human biotinidase isn't just for recycling biotin J. Nutr., 1999
Biotinidase and its roles in biotin metabolism Clin. Chim. Acta, 1996
Distribution and degradation of biotin-containing carboxylases in human cell lines Biochem. J., 1985