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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex

PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer + EPM2A dimer → EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer

Reactome: R-HSA-3781001
Compartment: cytosol
Rhea: None recorded

Inputs

PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramerR-HSA-3777093, cytosol
EPM2A dimerR-HSA-6805697, cytosol

Outputs

EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramerR-HSA-3780999, cytosol

Catalysed by

protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]

Literature

Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG) J. Biol. Chem., 2008