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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Autoglucosylation of GYG2 complexed with GYS2-a

8 UDP-Glc + GYG2:GYS2-a tetramer → 8 UDP + oligoGlc-GYG2:GYS2-a tetramer + 8 H+

Reactome: R-HSA-3322014
Compartment: cytosol
Rhea: RHEA:23361

Inputs

8 UDP-GlcCHEBI:58885, C15H22N2O17P2, cytosol
GYG2:GYS2-a tetramerR-HSA-3322031, cytosol

Outputs

8 UDPCHEBI:58223, C9H11N2O12P2, cytosol
oligoGlc-GYG2:GYS2-a tetramerR-HSA-3321999, cytosol
8 H+CHEBI:15378, H, cytosol

Catalysed by

glycogenin glucosyltransferase activity of GYG2:GYS2-a tetramer [cytosol]EC 2.4.1.186

Literature

Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis. J Biol Chem, 1997
Glycogen and its metabolism: some new developments and old themes Biochem. J., 2012