TCN1 binds correnoids in the circulation
TCN1 + correnoid → TCN1:correnoid
- Reactome
- R-HSA-3245898
- Compartment
- extracellular region
- Rhea
- None recorded
Inputs
- TCN1R-HSA-2980920, extracellular region
- correnoidCHEBI:33913, C19CoN4R21, extracellular region
Outputs
- TCN1:correnoidR-HSA-9758894, extracellular region
Catalysed by
- molecular sequestering activity of TCN1 [extracellular region]UniProt P20061
Literature
- Structural basis of transcobalamin recognition by human CD320 receptor Nat Commun, 2016
- Structural basis for universal corrinoid recognition by the cobalamin transport protein haptocorrin J Biol Chem, 2013
- Structure of the cDNA encoding transcobalamin I, a neutrophil granule protein J. Biol. Chem., 1989
- Absorption, plasma transport, and cellular retention of cobalamin analogues in the rabbit. Evidence for the existence of multiple mechanisms that prevent the absorption and tissue dissemination of naturally occurring cobalamin analogues J Clin Invest, 1977