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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

CBLIF binds RCbl

CBLIF + RCbl → CBLIF:RCbl

Reactome: R-HSA-3000120
Compartment: extracellular region
Rhea: None recorded

Inputs

CBLIFR-HSA-2980918, extracellular region
RCblCHEBI:140785, C62H88CoN13O14PR, extracellular region

Outputs

CBLIF:RCblR-HSA-3000147, extracellular region

Catalysed by

cargo receptor ligand activity of CBLIF [extracellular region]UniProt P27352

Literature

Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution Proc. Natl. Acad. Sci. U.S.A., 2007