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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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CD320-mediated TCN2:RCbl uptake and delivery to lysosome

TCN2:RCbl:CD320 → CD320 + TCN2:RCbl

Reactome
R-HSA-3000112
Compartment
plasma membrane · lysosomal lumen · extracellular region
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • cargo receptor activity of TCN2:RCbl:CD320 [plasma membrane]

Literature

  1. Structural basis of transcobalamin recognition by human CD320 receptor Nat Commun, 2016
  2. Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts Exp. Cell Res., 1979