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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

NADPH transfers electrons to FDXR

NADPH + FDXR:FAD + H+ → NADP+ + FDXR:FADH2

Reactome: R-HSA-2395517
Compartment: mitochondrial matrix
Rhea: None recorded

Inputs

NADPHCHEBI:57783, C21H26N7O17P3, mitochondrial matrix
FDXR:FADR-HSA-2395508, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Outputs

NADP+CHEBI:58349, C21H25N7O17P3, mitochondrial matrix
FDXR:FADH2R-HSA-2395502, mitochondrial matrix

Catalysed by

ferredoxin-NADP+ reductase activity of FDXR [mitochondrial matrix]EC 1.18.1.2; UniProt P22570

Literature

Expression and characterization of human mitochondrial ferredoxin reductase in Escherichia coli Arch. Biochem. Biophys., 1992