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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

COQ4 decarboxylates MHDB

MHDB + H+ → DMPhOH + CO2

Reactome: R-HSA-2162195
Compartment: mitochondrial matrix
Rhea: RHEA:81275

Inputs

MHDBCHEBI:62796, C58H87O4, mitochondrial inner membrane
H+CHEBI:15378, H, mitochondrial matrix

Outputs

DMPhOHCHEBI:50774, C57H88O2, mitochondrial inner membrane
CO2CHEBI:16526, CO2, mitochondrial matrix

Catalysed by

4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity of COQ3:COQ4:COQ5:COQ6:COQ7:COQ9 [mitochondrial inner membrane]EC 4.1.1.130

COQ4 decarboxylates MHDB

Inputs

Outputs

Catalysed by

Literature