Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

COQ3 methylates DeMQ10H2

DeMQ10H2 + AdoMet → CoQH2 + AdoHcy + H+

Reactome: R-HSA-2162186
Compartment: mitochondrial matrix
Rhea: RHEA:44412, RHEA:44413

Inputs

DeMQ10H2CHEBI:64182, C58H90O4, mitochondrial inner membrane
AdoMetCHEBI:59789, C15H23N6O5S, mitochondrial matrix

Outputs

CoQH2CHEBI:64183, C59H92O4, mitochondrial inner membrane
AdoHcyCHEBI:57856, C14H20N6O5S, mitochondrial matrix
H+CHEBI:15378, H, mitochondrial matrix

Catalysed by

3-demethylubiquinol 3-O-methyltransferase activity of COQ3:COQ4:COQ5:COQ6:COQ7:COQ9 [mitochondrial inner membrane]EC 2.1.1.64

COQ3 methylates DeMQ10H2

Inputs

Outputs

Catalysed by

Literature