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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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LXA4 is oxidised to 15k-LXA4 by HPGD

LXA4 + NAD+ → 15k-LXA4 + NADH + H+

Reactome
R-HSA-2161779
Compartment
cytosol
Rhea
RHEA:41573

Inputs

Outputs

Catalysed by

  • 15-hydroxyprostaglandin dehydrogenase (NAD+) activity of HPGD dimer [cytosol]EC 1.1.1.141

Literature

  1. Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation J Biol Chem, 2000