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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

NDST1-4 N-deacetylates GlcNAc residues in heparan

H2O + Heparan(3)-PGs → CH3COO- + Heparan(4)-PGs

Reactome: R-HSA-2022887
Compartment: Golgi membrane · Golgi lumen
Rhea: RHEA:70588

Inputs

H2OCHEBI:15377, H2O, Golgi lumen
Heparan(3)-PGsR-HSA-2076535, Golgi lumen

Outputs

CH3COO-CHEBI:30089, C2H3O2, Golgi lumen
Heparan(4)-PGsR-HSA-2076346, Golgi lumen

Catalysed by

N-acetylglucosamine deacetylase activity of NDSTs [Golgi membrane]EC 3.5.1.33

Literature