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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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3xPPCDC:3FMN decarboxylates PPC

PPC + H+ → PPANT + CO2

Reactome
R-HSA-196840
Compartment
cytosol
Rhea
RHEA:16794

Inputs

Outputs

Catalysed by

  • phosphopantothenoylcysteine decarboxylase activity of 3xPPCDC:3xFMN [cytosol]EC 4.1.1.36

Literature

  1. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics J Biol Chem, 2002
  2. Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent Biochemistry, 2004