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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

COASY transfers an adenylyl group from ATP to PPANT

ATP + H+ + PPANT → DP-CoA + PPi

Reactome: R-HSA-196754
Compartment: cytosol · mitochondrial outer membrane
Rhea: RHEA:19802

Inputs

ATPCHEBI:30616, C10H12N5O13P3, cytosol
H+CHEBI:15378, H, cytosol
PPANTCHEBI:61723, C11H21N2O7PS, cytosol

Outputs

DP-CoACHEBI:57328, C21H33N7O13P2S, cytosol
PPiCHEBI:33019, HO7P2, cytosol

Catalysed by

pantetheine-phosphate adenylyltransferase activity of COASY [mitochondrial outer membrane]EC 2.7.7.3; UniProt Q13057

COASY transfers an adenylyl group from ATP to PPANT

Inputs

Outputs

Catalysed by

Literature