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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

UROD decarboxylates URO1 to COPRO1

URO1 + 4 H+ → COPRO1 + 4 CO2

Reactome: R-HSA-190182
Compartment: cytosol
Rhea: RHEA:31240

Inputs

URO1CHEBI:62626, C40H36N4O16, cytosol
4 H+CHEBI:15378, H, cytosol

Outputs

COPRO1CHEBI:62631, C36H40N4O8, cytosol
4 CO2CHEBI:16526, CO2, cytosol

Catalysed by

carbon-carbon lyase activity of 2xUROD [cytosol]EC 4.1

UROD decarboxylates URO1 to COPRO1

Inputs

Outputs

Catalysed by

Literature