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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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XYLTs transfer Xyl to core protein

UDP-Xyl + GAG core proteins → UDP + xylosyl-core proteins + H+

Reactome
R-HSA-1878002
Compartment
Golgi membrane · Golgi lumen
Rhea
RHEA:50193

Inputs

Outputs

Catalysed by

  • protein xylosyltransferase activity of XYLT1, XYLT2 [Golgi membrane]EC 2.4.2.26

Literature

  1. Analysis of the DXD motifs in human xylosyltransferase I required for enzyme activity J Biol Chem, 2004
  2. Human xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activity Biochem J, 2005
  3. Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II J Mol Biol, 2000
  4. XT-II, the second isoform of human peptide-O-xylosyltransferase, displays enzymatic activity J. Biol. Chem., 2007