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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases

SUMF1 + SUMF2 → SUMF1:SUMF2

Reactome: R-HSA-1614336
Compartment: endoplasmic reticulum lumen
Rhea: None recorded

Inputs

SUMF1R-HSA-1614316, endoplasmic reticulum lumen
SUMF2R-HSA-1614305, endoplasmic reticulum lumen

Outputs

SUMF1:SUMF2R-HSA-1614330, endoplasmic reticulum lumen

Catalysed by

enzyme inhibitor activity of SUMF2 [endoplasmic reticulum lumen]UniProt Q8NBJ7

Literature