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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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GLB1 hydrolyzes SapB/C:LacCer

H2O + Sap B/C:LacCer → Gal + Sap B/C:GlcCer

Reactome
R-HSA-1606312
Compartment
lysosomal lumen
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • beta-galactosidase activity of BGAL [lysosomal lumen]EC 3.2.1.23

Literature

  1. Human small-intestinal beta-galactosidases. Separation and characterization of one lactase and one hetero beta-galactosidase Biochem J, 1969
  2. Emerging concepts of ganglioside metabolism FEBS Lett, 2018
  3. Prosaposin deficiency: further characterization of the sphingolipid activator protein-deficient sibs. Multiple glycolipid elevations (including lactosylceramidosis), partial enzyme deficiencies and ultrastructure of the skin in this generalized sphingolipid storage disease Hum Genet, 1993