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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Salvage - BH2 is reduced to BH4 by DHFR

q-BH2 + H+ + NADPH → BH4 + NADP+

Reactome
R-HSA-1497794
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • dihydrofolate reductase activity of DHFR dimer [cytosol]EC 1.5.1.3

Literature

  1. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways J Biol Chem, 2009