Skip to content

DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Frataxin binds iron

FXN:ISD11:NFS1:ISCU + 4 Fe2+ → 2 Iron:FXN:NFS1:ISD11:ISCU

Reactome: R-HSA-1362416
Compartment: mitochondrial matrix
Rhea: None recorded

Inputs

FXN:ISD11:NFS1:ISCUR-HSA-1362404, mitochondrial matrix
4 Fe2+CHEBI:29033, Fe, mitochondrial matrix

Outputs

2 Iron:FXN:NFS1:ISD11:ISCUR-HSA-1362401, mitochondrial matrix

Catalysed by

ferrous iron binding activity of FXN:ISD11:NFS1:ISCU [mitochondrial matrix]

Literature